I must first underscore the difficulties with playing Pot of Greed in Genesys, as well as give some insight as to what constitutes a successful gameplan nowadays
Unless this task has been completed, it enters play with its weakness side faceup
In recent years, both of their effects have had the same change added to them, in that the Monsters they search from the Main Deck can't use their effects for the rest of the turn, as well as limiting Sangan and Witch of the Black Forest to a hard "once per turn" limit
Bumbleflower Perrie, the Pulverizer Phelddagrif Rafiq of the Many Ragnar Rigo, Streetwise Mentor Roon of the Hidden Realm Rubinia Soulsinger Shanna, Purifying Blade Shaun & Rebecca, Agents Sophia, Dogged Detective Storvald, Frost Giant Jarl Surris, Silk-Tech Vanguard Tidus, Yuna's Guardian Tocasia, Dig Site Mentor Treva, the Renewer Tuvasa the Sunlit Yuna, Grand Summoner
Lets gear up and dive in
If your opponent is ahead of you and close to victory, you could potentially force them to drop a stacked had of support for a single card