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JAK2 and JAK3 with IC50 of 0
CAS Number: 1835705-55-9
Formula: C15H17ClN6O3
Smiles: CCCCCCCC1=CC(O)=C2C=CC=CC2=[N+]1[O-]
lesions to stable fibromuscular lesions in vivo
Eltanexor (KPT-8602) Size:Contact [email protected] for quotation JAK2 and JAK3 with IC50Eltanexor, also known as KPT 8602, is a second generation exportin 1 inhibitor. KPT 8602 demonstrates potent activity against acute lymphoblastic leukemia. KPT 8602 is well tolerated and highly active against AML blasts and leukemia initiating cells. Eltanexor shows improved efficacy and in vivo tolerability in hematological malignancies. KPT 8602 is a potent inhibitor of AML cells in cell based viability assays. KPT 8602 inhibits XPO1 cargo