ML-7 Hydrochloride - CAS# 110448-33-4 curcumin 4R)-4-[(diaminomethylidene)amino]-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid

4R)-4-[(diaminomethylidene)amino]-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid

Smiles: OC(=O)C1=CC2=C(C=C1)C1(OC2=O)C2=CC=C(O)C=C2OC2=CC(O)=CC=C12

Smiles: OC1=CC2OC(=O)C3=CC=CC=C3C=2C=C1

7(12): e50638

CAS Number: 1337532-29-2

ML-7 Hydrochloride - CAS# 110448-33-4 curcumin 4R)-4-[(diaminomethylidene)amino]-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acidML 7 is a MLCK inhibitor. ML 7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0. 3 M. ML 7 amplifies the quinocetone induced cell death through akt and MAPK mediated apoptosis on HepG2 cell line. ML 7 inhibits exocytosis of superoxide producing intracellular compartments in human neutrophils stimulated with phorbol myristate acetate in a myosin light chain kinase independent manner. Product information CAS Number: 110448 33