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the positive control
WO2016142049A1
A-779 in the OVX animals does not change AngII
InChiKey: CHMQQIFPOIZPIJ-UHFFFAOYSA-N
InChi: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7
Benzamil hydrochloride G3-C2-NH2 TFA the positive controlBenzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+ Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non selective Deg epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3 mediated Ca2+ activated currents, with an IC50 of 1. 1 M. Product information CAS Number: 161804 20 2 Molecular Weight: 356. 21 Formula:
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