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Smiles: CC1C=C(NC(=O)C(=O)C2C=C(CC3C=CC(=CC=3)C#N)N3C=CC=CC3=2)SN=1
CC1C=CC=C(C)C=1NC(=O)C[N+](CC)(CC)CC
GNE684 (20 μM
8 ng/mL (mean) to undetectable levels
24)25/h1-6
Trap-101 hydrochloride rtan (Cilexetil) Smiles: CC1C=C(NC(=O)C(=O)C2C=C(CC3C=CC(=CC=3)C#N)N3C=CC=CC3=2)SN=1Trap 101 hydrochloride is a potent, selective and competitive antagonist of NOP receptors over classical opioid receptors. Trap 101 stimulates GTP35S binding to CHOhNOP membranes with pKi values of 8. 65, 6. 60, 6. 14 and <5 for NOP, , , and opioid receptors, respectively. Trap 101 attenuates motor deficits in a rat model of parkinson's disease and can be used for the research of nervous system diseases. Product information CAS Number: 1216621 00 9
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