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It is potent in most cancer cell lines
was first identified and reported by a group scientists from Korea
774549-97-2
293(19):7476-7485
CAS Number: 3326-34-9
Necrostatin-1 Size:Solid 2 mg It is potent in mostNecrostatin 1 is a potent and selective inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin 1 functions as an allosteric inhibitor of the death domain receptor associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin 1 does not present any perturbation of the Fas TNFR triggered canonical apoptosis cascade. Necrostatin 1 inhibits RIP1
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