IDH1 Inhibitor 1 Catalog No.:M24963-C 90 days) shows no toxicity

90 days) shows no toxicity on SD rats

Smiles: O=C1NC(=O)C(NC2C=CC=CC=2)=C1C1=CN(CCCN2C=NC=C2)C2=CC=CC=C21

Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level

InChiKey: VAIOZOCLKVMIMN-PRJWTAEASA-N

Chemical Name: (5Z)-5-[(3-bromo-4-hydroxyphenyl)methylidene]-3-(4-methoxyphenyl)-2-sulfanylidene-1

IDH1 Inhibitor 1 Catalog No.:M24963-C 90 days) shows no toxicityIDH1 Inhibitor 1 is a potent, orally bioavailable, brain penetrant and selective mutant IDH1 inhibitor with IC50s of 0. 021 M, 0. 045 M, and 2. 52 M for IDH1R132H, IDH1R132C, and IDH1WT, respectively. Anticancer activity. Product information CAS Number: 2234285 81 3 Molecular Weight: 450. 39 Formula: C20H18F4N6O2 Chemical Name: (4R) 4 (fluoromethyl) 3 (2 {[(1S) 1 {1 [4 (trifluoromethyl)phenyl] 1H imidazol 4 yl}ethyl]amino}pyrimidin 4 yl) 1,3