PFI-3 - SMARCA Bromodomains Inhibitor. CAS# 1819363-80-8 Catalog No.:M60175-10S FH1 was suggested to be

FH1 was suggested to be supplemented into the culture medium on day 21 at a concentration of 15-20 μM to enhance hepatocyte functions in vitro over period of 9 days

9(4):247-9

and inhibits the growth of two xenografted tumors in mice in vivo

(2010) Cell 142(1)

P7C3 Neuroprotective Chemicals Function by Activating the Rate-Limiting Enzyme in NAD Salvage

PFI-3 - SMARCA Bromodomains Inhibitor. CAS# 1819363-80-8 Catalog No.:M60175-10S FH1 was suggested to bePFI 3, CAS No. 1819363 80 8, is a novel potent, selective and cell permeable inhibitor of SMARCA4 and PB1(5) bromodomains with IC50 ~ 89 nM and 48 nM respectively. It also inhibits SMARCA2, but has no interaction with the other sub family branches including PB1(2 4) and a kinase panel of 36 kinases. It accelerates FRAP recovery in cells at a concentration of 1 M. The SWI SNF related, Matrix associated, Actin dependent Regulator of Chromatin (SMARC)