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2019 Apr 2
YL0919 shows affinities to rat 5-HT1A receptors
4S)-4-[(2-methylpropanoyl)oxy]pent-2-enamido]oxan-2-yl]-3-methylpenta-1
InChi: InChI=1S/C23H20F2N2O4/c1-11-15-5-2-12(8-13(15)9-26-11)16-6-7-17-19(21(16)31-23(24)25)27(14-3-4-14)10-18(20(17)28)22(29)30/h2
1034148-04-3
(3S, 4S)-PF-06459988 03 (methanesulfonate) 2019 Apr 2(3S, 4S) PF 06459988 is the S enantiomer of PF 06459988 with less active. PF 06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF 06459988 has excellent selectivity against EGFR wild type while possessing a minimally reactive electrophile that reduces the propensity of off target labeling. Product information CAS Number: 1858291 14 1 Molecular Weight: 431. 88 Formula: C19H22ClN7O3 Chemical Name: 1
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