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1155/2015/813816
InChiKey: MPDGHEJMBKOTSU-YKLVYJNSSA-N
the oral bioavailability is 90%
Smiles: CC1C=C(C)C(=CC=1)C1=CSC(NC(=O)C2C=CC=CC=2)=N1
Trimethylamine N-Oxide: The Good
Enpatoran hydrochloride Size:Contact [email protected] for quotation 1155/2015/813816Enpatoran (M5049) hydrochloride is a potent, orally active and dual TLR7 8 inhibitor with IC50s of 11. 1 nM and 24. 1 nM in HEK293 cells, respectively. Enpatoran hydrochloride is inactive against TLR3, TLR4 and TLR9. Enpatoran hydrochloride can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran hydrochloride exhibits excellent pharmacokinetic properties in vivo. Enpatoran hydrochloride can be used for both innate and