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Antiinflammatory constituents from the roots of Smilax bockii warb
with GI50 less than 100 nM
Highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC50 = 1
10H-cycloocta[b]pyran-3-yl})methyl]phenyl}benzene-1-sulfonamide
8-dihydroxy-6-methoxy-2H-chromen-2-one
HE-3235 5217 Antiinflammatory constituents from the rootsHE 3235 is a novel antagonist of androgen receptor. Androgen receptor (AR) is an adrenal hormone belongs to the steroid hormone receptor family of molecules. AR is responsible for mediating the physiologic effects of androgens by binding to specific DNA sequences that influence transcription of androgen responsive genes. Variations in the AR gene may lead to genetic predisposition to prostate cancer development and severity . In vitro: In LNCaP cells
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