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Naratriptan is a selective 5-HT1 receptor subtype agonist for the treatment of migraine headache
InChiKey: IHHMUBRVTJMLQO-UHFFFAOYSA-N
14-hexaen-10-one
Formula: C30H30ClN3O4
KY02111 was used at 10 µM final concentration in vitro and in cellular assays
Ro 25-6981 Size:Solid 2 mg Naratriptan is a selective 5-HT1Ro 25 6981 is a highly potent and selective blocker of N methyl D aspartate receptors containing the NR2B subunit. Ro 25 6981 inhibited 3H MK 801 binding to rat forebrain membranes in a biphasic manner with IC50 values of 0. 003 microM and 149 microM for high (about 60%) and low affinity sites, respectively. NMDA receptor subtypes expressed in Xenopus oocytes were blocked with IC50 values of 0. 009 microM and 52 microM for the subunit combinations
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