MAP4K4-IN-3 Catalog No.:M12309-2 InChi: InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57

InChi: InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57

Chemical Name: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine hydrochloride

Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway

Lometrexol (1-30 μM

ClH/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20

MAP4K4-IN-3 Catalog No.:M12309-2 InChi: InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57MAP4K4 IN 3 (Compound 17) is a potent and selective MAP4K4 inhibitor with an IC50 of 14. 9 nM in kinase assay, an IC50 of 470 nM in cell assay. Antidiabetic agent. Product information CAS Number: 1811510 58 3 Molecular Weight: 297. 74 Formula: C15H12ClN5 Chemical Name: 5 [6 amino 5 (4 chlorophenyl)pyridin 3 yl]pyrimidin 2 amine Smiles: NC1=NC=C(C=C1C1C=CC(Cl)=CC=1)C1C=NC(N)=NC=1 InChiKey: KSQDIECZAQKQQW UHFFFAOYSA N InChi: InChI=1S C15H12ClN5 c16 12 3