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ENMD-2076 tartrate - CAS# 1291074-87-7 lol metabolite 4-Hydroxyphenyl Carvedilol PubMed PMID: 23828641

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Description

PubMed PMID: 23828641

InChi: InChI=1S/C22H16F4N6O2/c23-16-6-5-12(10-17-13-3-1-2-4-14(13)19(33)29-28-17)9-15(16)20(34)31-7-8-32-18(11-31)27-21(30-32)22(24

PMID: 31927622

Molecular Weight: 347

CN(C)C(=O)OC1C=CC=[N+](C)C=1

ENMD-2076 tartrate - CAS# 1291074-87-7 lol metabolite 4-Hydroxyphenyl Carvedilol PubMed PMID: 23828641ENMD 2076 is an orally active, Aurora A angiogenic kinase inhibitor with a unique kinase selectivity profile and multiple mechanisms of action. ENMD 2076 has been shown to inhibit a distinct profile of angiogenic tyrosine kinase targets in addition to the Aurora A kinase. Aurora kinases are key regulators of mitosis (cell division), and are often over expressed in human cancers. ENMD 2076 also targets the VEGFR, Flt 3 and FGFR3 kinases which have been

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