2, 6-Dimethylhydroquinone 8463 including drug- and multidrug-resistant and

including drug- and multidrug-resistant and p53-deficient cell lines

Sabine Bachmaier

selective and irreversible FASN inhibitor with an IC50 of 0

2S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-2-carbamoyl-1-{[({2-[(2S)-2-{[(1S)-1-{[(1S)-1-[({[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-{[(1S)-1-carbamoyl-2-hydroxyethyl]carbamoyl}pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}methyl)carbamoyl]-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}carbamoyl)methyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-3-carboxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-phenylethyl]carbamoyl}-3-methylbutyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-methylpropyl]carbamoyl}ethyl]carbamoyl}-3-carboxypropyl]carbamoyl}-3-carboxypropyl]carbamoyl}-3-carboxypropyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}pentyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-carboxyethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}methyl)carbamoyl]-4-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}butanoic acid

Meptazinol is a 3-phenylazpane derivative

2, 6-Dimethylhydroquinone 8463 including drug- and multidrug-resistant and2,6 Dimethylhydroquinone is an endogenous metabolite. Product information CAS Number: 654 42 2 Molecular Weight: 138. 16 Formula: C8H10O2 Chemical Name: 2,6 dimethylbenzene 1,4 diol Smiles: CC1C=C(O)C=C(C)C=1O InChiKey: SGWZVZZVXOJRAQ UHFFFAOYSA N InChi: InChI=1S C8H10O2 c1 5 3 7(9)4 6(2)8(5)10 h3 4,9 10H,1 2H3 Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis) Shipping Condition: Shipped under ambient