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AVL-292 (benzenesulfonate) X-222 PubMed PMID: 23650921

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Description

PubMed PMID: 23650921

56(1455):111-2

compared with other receptor tyrosine kinases

ortho-iodoHoechst 33258 is part of a family of blue fluorescent dyes used to stain DNA

2011 Feb 15

AVL-292 (benzenesulfonate) X-222 PubMed PMID: 23650921Spebrutinib, also known as AVL 292 or CC 292, is an orally bioavailable, selective inhibitor of Brutons agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL 292 targets and covalently binds to BTK, thereby preventing its activity. Product information CAS Number: 1360053 81 1 Molecular Weight: 581. 62 Formula: C28H28FN5O6S Synonym: Spebrutinib besylate CC 292 besylate Chemical Name: N {3 [(5 fluoro

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