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ZXH-3-26 is a selective PROTAC BRD4 degrader
GSK650394 inhibits SGK1-mediated epithelial transport with an IC50 of 0
AMI-1 was used at 10-30 µM final concentration in vitro and in cellular assays
ZK824190 is an orally available and selective urokinase plasminogen activator (uPA) inhibitor as a potential treatment for multiple sclerosis
is a potent and selective Rho kinase inhibitor
PHA-680632 182 ZXH-3-26 is a selective PROTACPHA 680632 is a is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. PHA 680632 is also the first representative of a new class of Aurora inhibitors with a high potential for further development as an anticancer therapeutic. PHA 680632 is active on a wide range of cancer cell lines and shows significant tumor growth inhibition in different animal tumor models at well tolerated doses. Product
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