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Palbociclib isethionate nate Sodium CAS Number: 6429-04-5

SKU: 22807781331

4.6
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Description

CAS Number: 6429-04-5

975 μg/mL

also known as ingenol-3-angelate

Ishikawa T

to the same extent as S6K1 and Akt phosphorylation

Palbociclib isethionate nate Sodium CAS Number: 6429-04-5Palbociclib, also known as PD 0332991, is an orally available cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib selectively inhibits cyclin dependent kinase 4 (CDK4) and 6 (CDK6), thereby inhibiting retinoblastoma (Rb) protein phosphorylation early in the G1 phase leading to cell cycle arrest. This suppresses DNA replication and decreases tumor cell proliferation. CDK4 and 6 are serine threonine kinases that

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