Lenalidomide-5-Br 2601 completely abrogating HIF-1α induction at

completely abrogating HIF-1α induction at ≥10 μM concentrations

2011 Nov 18

Vinogradova M

β-Amyloid (31-35) increases the phosphorylation of biotinylated Aβ(1-40)

Smiles: CC(=O)O[C@]12[C@H]3[C@@H](OC(=O)C4C=CC=CC=4)[C@](O)(C[C@H]3[C@]34[C@H]5C(OC)[C@H]1[C@H]3N(C[C@]5(COC)[C@H](O)C[C@@H]4OC)CC)[C@@H](OC)[C@@H]2O

Lenalidomide-5-Br 2601 completely abrogating HIF-1α induction atLenalidomide 5 Br is the Lenalidomide based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide 5 Br can be connected to the ligand for protein by a linker to form PROTAC. Product information CAS Number: 1010100 26 1 Molecular Weight: 323. 14 Formula: C13H11BrN2O3 Chemical Name: 3 (5 bromo 1 oxo 2,3 dihydro 1H isoindol 2 yl)piperidine 2,6 dione Smiles: O=C1CCC(C(=O)N1)N1CC2C=C(Br)C=CC=2C1=O InChiKey: CMRQAKJTXKOGSF UHFFFAOYSA