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4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]-4-hydroxyoxolan-2-yl]methoxy}phosphonic acid
CAS Number: 22189-32-8
PubMed PMID: 15479895
VU0467485 (1-10 mg/kg
OSU-03012 induces apoptotic death in PC-3 cells with IC50 of 5 µM and reduces the activity of immunoprecipitated p70S6K
PF-06305591 206Cyclodextrin 4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]-4-hydroxyoxolan-2-yl]methoxy}phosphonic acidPF 06305591 is a potent and highly selective voltage gated sodium channel NaV1. 8 blocker, with an IC50 of 15 nM. An excellent preclinical in vitro ADME and safety profile. Product information CAS Number: 1449473 97 5 Molecular Weight: 274. 36 Formula: C15H22N4O Chemical Name: (2R,3S) 3 amino 3 (5 tert butyl 1H 1,3 benzodiazol 2 yl) 2 methylpropanamide Smiles: C[C@H]([C@H](N)C1NC2=CC=C(C=C2N=1)C(C)(C)C)C(N)=O InChiKey: APWZIFIAVVFPNT PELKAZGASA N