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EGFR-IN-1 14 mesylate InChiKey: FCEVNJIUIMLVML-QPSVUOIXSA-N

SKU: 249698543

4.9
USD100.00 USD139.00

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Description

InChiKey: FCEVNJIUIMLVML-QPSVUOIXSA-N

Selectivity testing against a panel of 7 transmembrane domain receptors indicated that BX 513 is inactive on a number of receptors at concentrations up to 10 μM

another agonist with predominant 5-HT2 actions

their biological effects and potential molecular targets

At the transfected human α4β2 neuronal nAChR in K177 cells

EGFR-IN-1 14 mesylate InChiKey: FCEVNJIUIMLVML-QPSVUOIXSA-NEGFR IN 1 (compound 24) is an orally active and irreversible L858R T790M mutant selective EGFR inhibitor. EGFR IN 1 potently inhibits Gefitinib resistant EGFR L858R, T790M with 100 fold selectivity over wild type EGFR. EGFR IN 1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity. Product information CAS Number: 1625677 63 5 Molecular Weight: 514. 58 Formula: C28H30N6O4 Chemical

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