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Ro5-3335 inhibits definitive hematopoiesis in zebrafish embryos
Smiles: CC1N=C(NC(C=1C(=O)OC)C1=CC=C(F)C=C1Cl)C1=NC=C(F)C=C1F
InChiKey: KAGBHVBIOJBGBD-NINOIYOQSA-N
daily for 35 days) treatment shows the average tumor volume in mice 82% smaller than that in the control group
CYP2A6 and CYP2E1 with IC50 values of 24 µM and 42 µM
SAR-260301 C BET Degrader-1 Ro5-3335 inhibits definitive hematopoiesis inSAR 260301 is an orally available and selective PI3K inhibitor with an IC50 of 23 nM. Product information CAS Number: 1260612 13 2 Molecular Weight: 354. 40 Formula: C19H22N4O3 Chemical Name: 2 {2 [(2S) 2 methyl 2,3 dihydro 1H indol 1 yl] 2 oxoethyl} 6 (morpholin 4 yl) 1,4 dihydropyrimidin 4 one Smiles: C[C@H]1CC2C=CC=CC=2N1C(=O)CC1NC(=CC(=O)N=1)N1CCOCC1 InChiKey: UAXHPOBBKRWJGA ZDUSSCGKSA N InChi: InChI=1S C19H22N4O3 c1 13 10 14 4 2 3 5