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and displays a favorable cytotoxicity profile toward normal cells
This short-duration GHS was orally active in canine models and was selected as a development candidate for the treatment of musculoskeletal frailty in elderly adults
2001 Jan 23
PF-5274857 is a potent
Epub 2013 Feb 7
AG-1478 Size:Solid 10 mg and displays a favorable cytotoxicityProtein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTK. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor receptor (EGFR) kinase and block EGFR dependent cell proliferation. AG 1478 is an inhibitor of EGFR kinase with an IC50 value of 3 nM. 1 Due to its potency and selectivity,
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