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C-021 dihydrochloride dium formononetin-3'-sulfonate respectively) and is inactive against

SKU: 27232509304

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Description

respectively) and is inactive against a general panel of over 200 kinases when tested at 10 µM

Dihydrexidine competes stereoselectively and potently for D1 binding sites in rat striatal membranes labeled with [3H]SCH23390 with an IC50 of about 10 nM compared to about 30 nM for the prototypical D1 agonist SKF38393

InChiKey: YWXYYJSYQOXTPL-SLPGGIOYSA-N

Chemical Name: N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide hydrochloride

Chemical Name: (3Z)-N-(3-fluorophenyl)-6

C-021 dihydrochloride dium formononetin-3'-sulfonate respectively) and is inactive againstC 021 dihydrochloride is a potent CC chemokine receptor 4 (CCR4) antagonist. C 021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C 021 effectively prevents human CCL22 derived [35S]GTPS from binding to the receptor with an IC50 of 18 nM. Product information CAS Number: 1784252 84 1 Molecular Weight: 540. 57 Formula: C27H43Cl2N5O2 Chemical Name: (4E) 2 {[1,4' bipiperidin] 1' yl}

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