Pay in 4 interest-free payments of $16.25 Learn more
Ships within 48 hours · Estimated delivery Oct 10 - Oct 15
Enasidenib
Molecular Weight: 261
selective and cell permeable BRPF1 bromodomain inhibitor with IC50 ~ 80 nM
It inhibited phosphorylation of NRAS (major isoform of Ras family) with IC50 value of 24nM
It can be found in Allophylus edulis and in the serum left after the coagulation of the Hevea brasiliensis latex in the operation of rubber tapping
APX-115 free base - CAS# 1270084-92-8 size:10mg solid EnasidenibAPX 115 free base, CAS No. 1270084 92 8, also known as EWHA 18278, is a potent, orally active pan NADPH oxidase (Nox) inhibitor. APX 115 protects development of diabetic nephropathy in podocyte specific NOX5 transgenic mice. APX 115 might be a promising therapeutic agent for the treatment of DN because of its pan NOX inhibitory activity, including its NOX5 inhibitory activity, and also owing to its anti inflammatory effect. Product information CAS