Ponesimod bersonine hydrochloride Tephrosin induces degradation of of

Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors

49)/b21-20+/t30-

CAS Number: 4630-07-3

H2O : 10 mg/mL (14

Juan-Garcia A

Ponesimod bersonine hydrochloride Tephrosin induces degradation of ofPonesimod (ACT 128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1 mediated signal transduction with high potency (EC50=5. 7 nM). Ponesimod can protect against lymphocyte mediated tissue inflammation. Product information CAS Number: 854107 55 4 Molecular Weight: 460. 97 Formula: C23H25ClN2O4S Chemical Name: (2E,5Z) 5 ({3 chloro 4 [(2S) 2,3