SR-1114 Catalog No.:M33701-C Smiles: CC(C)=CC(=O)CCC(=O)N1CCN(CC2=CC3=NC(=NC(=C3S2)N2CCOCC2)C2C=CC=C3NN=CC=23)CC1

Smiles: CC(C)=CC(=O)CCC(=O)N1CCN(CC2=CC3=NC(=NC(=C3S2)N2CCOCC2)C2C=CC=C3NN=CC=23)CC1

4 nM for BaF3-VEGFR-2

Chemical Name: 2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one

]tetracontane-3

and Rispenzepine (M1/M3) on cholinergic neural contractile responses evoked by electrical field stimulation (EFS) and [3H]ACh release

SR-1114 Catalog No.:M33701-C Smiles: CC(C)=CC(=O)CCC(=O)N1CCN(CC2=CC3=NC(=NC(=C3S2)N2CCOCC2)C2C=CC=C3NN=CC=23)CC1SR 1114 is a first in class PROTAC ENL degrader. SR 1114 elicits rapid, CRBN dependent degradation of ENL with DC50s of 150 nM, 311 nM, and 1. 65 M in MV4; 11 , MOLM 13, and OCI AML 2 cells, respectively. Product information CAS Number: 2769141 82 2 Molecular Weight: 830. 86 Formula: C39H42N8O11S Smiles: O=S(=O)(NC1=CC=CC(=C1)C1=CN2C=C(C=CC2=N1)C(=O)NC1CCC1)NCCOCCOCCNC(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: WPVVPCVQEBQVLL UHFFFAOYSA N