AN-2690 Size:Solid 2 mg Chemical Name: 3-[(3R)-3-(4-fluorobenzenesulfonamido)-2

Chemical Name: 3-[(3R)-3-(4-fluorobenzenesulfonamido)-2

a ～3- to 4-fold increase in potency as an agonist for N- and P/Q-type Ca2+ channels

Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists

CC(=O)N[C@H]([C@H]1[C@@H](C[C@@H]([C@H]1O)C(O)=O)N=C(N)N)C(CC)CC

8 hours in rat and 2

AN-2690 Size:Solid 2 mg Chemical Name: 3-[(3R)-3-(4-fluorobenzenesulfonamido)-2Tavaborole, also known as AN 2690 (trade name Kerydin) is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed. Tavaborole began its Phase 3 trials in December 2010 and was approved in July 2014. Tavaborole inhibits an essential fungal enzyme, Leucyl tRNA synthetase, or LeuRS, required for protein synthesis. The inhibition of protein synthesis leads to termination of cell growth and cell