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124(6):1463-9
selective and oral bioactive agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5)
Both Endomorphin 1 and Endomorphin 2 display a profile similar to morphine
InChiKey: OKJBKEQXKMMRPL-WVILEFPPSA-N
CAS Number: 1401966-69-5
N-acetyl-2-carboxy Benzenesulfonamide 10766 124(6):1463-9IC50: 0. 06 and 0. 25 M for COX 1 and COX 2, respectively N acetyl 2 carboxy Benzenesulfonamide is a non selective inhibitor of COX. Pharmaceutical inhibition of COX is able to provide relief from the symptoms of inflammation and pain. Nonsteroidal anti inflammatory drugs, such as aspirin, exert its effect via inhibition of COX. In vitro: Previous in vitro COX 1 COX 2 inhibition studies showed that N acetyl 2 carboxy benzenesulfonamide was a more
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