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Int J Risk Saf Med
it is taken in order to prevent or at least reduce the occurrence of angina
ITI-214 exhibited picomolar inhibitory potency for PDE1
2016 Nov 18
InChiKey: XLSYZSRXVVCHLS-UHFFFAOYSA-N
PF-04449913 0 Racemate Int J Risk Saf MedGlasdegib, also known as PF 04449913, is an orally bioavailable small molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Hedgehog inhibitor PF 04449913 appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. Product