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in essential oils
PLX647 (30 mg/kg) results in significant inhibition of TRAP5b immunostaining and bone osteolysis
Formula: C26H36N6O2
Smiles: CN(C)C[C@@H](NC(=O)N1CC2C(NC(=O)C3C=CC(=CC=3)NC(=O)C=C)=NNC=2C1(C)C)C1C=CC=CC=1
YS-49 (10-100 μM
Calcipotriol - CAS# 112965-21-6 0591 in essential oilsCalcipotriol, a synthetic derivative of calcitriol or Vitamin D, is used in the treatment of psoriasis and marketed under the trade name Dovonex. It has comparable affinity with calcitriol (Vit. D) for the Vitamin D receptor (VDR), while being less than 1% as active as the calcitriol in regulating calcium metabolism. Chronic plaque psoriasis is the chief medical use of calcipotriol. It has also been used successfully in the treatment of alopecia
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