Like other methylated xanthine derivatives
Suggesting that PD-1/PD-L1-IN-10 (compound B2) could enter LLC cells and then directly binds to the PD-L1 protein
This leads to the ubiquitination of certain substrate proteins and induces the proteasome-mediated degradation of certain transcription factors
N[C@@H](CN1C=C(F)C(=O)NC1=O)C(O)=O
TMPRSS2 and FKBP5 in both LNCaP and VCaP cells
HS-131 nel Like other methylated xanthine derivativesHS 131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene driven breast cancers, including multiple different molecular subtypes of human breast cancers. Product information CAS Number: 2084850 40 6 Molecular Weight: 1318. 68 Formula: C71H95N7O13S2 Chemical Name: 2 [(1E, 3Z) 3 [4 (21 {[2 carbamoyl 5 (3, 6, 6 trimethyl 4 oxo 4, 5, 6, 7 tetrahydro 1H indazol 1 yl)phenyl]amino} 6, 9, 12, 15, 18 pentaoxa 2 azahenicosan 1 yl)phenyl]