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7-Chlorokynurenic acid Size:Contact [email protected] for quotation blocked EGF-stimulated autophosphorylation of the

SKU: 33788528931

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Description

blocked EGF-stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM)

First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes

5-A-RU-PABC-Val-Cit-Fmoc is the prodrug of 5-A-RU

PF-04217903 treatment (2 μM) increased cell death of GTL-16 cells

Formula: C27H43Cl2N5O2

7-Chlorokynurenic acid Size:Contact [email protected] for quotation blocked EGF-stimulated autophosphorylation of the7 Chlorokynurenic acid (7 CKA) is a potent and selective antagonist of the glycine B coagonist site of the N methyl D aspartate (NMDA) receptor (IC50=0. 56 M). 7 Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0. 59 M. 7 Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery. Product information CAS Number: 18000 24 3 Molecular Weight: 223. 61 Formula:

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