MARK-IN-1 fluorophenyl)-2-hydroxy-1-methyl-3-(1H-1 2 4-triazol-1-yl)propyl]benzamide-d3 5)44-29)36(19

5)44-29)36(19

1 mg/kg (n=16) Zatosetron maleate

incorporates an IAP ligand plus an amide-PEG5 linker with terminal amine ready for conjugation to a target protein ligand

Insights into the zinc-dependent deacetylase LpxC: biochemical properties and inhibitor design

In vitro: Phthalazinone pyrazole potently inhibited the activity of Aurora A kinase with an IC50 of 31 nM

MARK-IN-1 fluorophenyl)-2-hydroxy-1-methyl-3-(1H-1 2 4-triazol-1-yl)propyl]benzamide-d3 5)44-29)36(19MARK IN 1 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of <0. 25 nM. Product information CAS Number: 1109283 93 3 Molecular Weight: 471. 53 Formula: C22H23F2N7OS Chemical Name: N [(1R,6R) 6 amino 2,2 difluorocyclohexyl] 5 methyl 4 [6 (1 methyl 1H pyrazol 4 yl)pyrazolo[1,5 a]pyrimidin 3 yl]thiophene 2 carboxamide Smiles: CN1C=C(C=N1)C1=CN2N=CC(=C2N=C1)C1C=C(SC=1C)C(=O)N[C@@H]1[C@H](N)CCCC1(F)F InChiKey: