Rilmenidine - CAS# 54187-04-1 Size:10mg solid WP1130 was used at 5-10

WP1130 was used at 5-10 µM final concentration in various in vitro assays

Flavopiridol also potently inhibits the activity of Glycogen synthase kinase-3 (GSK-3) with an IC50 of 280 nm

UNC0379 was used at 10-30 µM in vitro assays

Phentolamine Analogue 1

is an orally bioavailable small molecule with potential antineoplastic activity

Rilmenidine - CAS# 54187-04-1 Size:10mg solid WP1130 was used at 5-10Rilmenidine, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine is an alpha 2 adrenoceptor agonist. Rilmenidine induces autophagy. Rilmenidine acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na+ H+ antiport. Rilmenidine modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway