URB597 Size:2mg solid Smiles: COC1C=C(NC2=NC3=CC=CC=C3N=C2NS(=O)(=O)C2C=C(C=CC=2)NC(=O)C(C)(C)N)C(Cl)=CC=1

Smiles: COC1C=C(NC2=NC3=CC=CC=C3N=C2NS(=O)(=O)C2C=C(C=CC=2)NC(=O)C(C)(C)N)C(Cl)=CC=1

AF-353 (Ro-4) also blocks human P2X2/3 channel function with marginally reduced potency with a p50 of 7

446(1-3):177-85

CAS Number: 90141-22-3

Solubility: DMSO: 74 mg/mL(199

URB597 Size:2mg solid Smiles: COC1C=C(NC2=NC3=CC=CC=C3N=C2NS(=O)(=O)C2C=C(C=CC=2)NC(=O)C(C)(C)N)C(Cl)=CC=1URB597, also known as KDS 4103, is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH). FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery where it activates cannabinoid receptors. In pre clinical laboratory tests researchers found URB597 increased the production of endocannabinoids resulting in