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or EBC1 (non-amplified
Smiles: CCCC1C=CC(=CC=1)OCC(=O)N(CC1=NC(=NO1)C1=CN=CC=C1)C(C)C
3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-oxadiazol-3-yl]benzoic acid
Formula: C30H34N8
Ro 48-8071 fumarate - CAS# 189197-69-1 Size:Solid 10 mg or EBC1 (non-amplifiedRo 48 8071 is an orally active cholesterol synthesis inhibitor or a 2,3 oxidosqualene: lanosterol cyclase (OSC) inhibitor. OSC (EC 5. 4. 99. 7) represents a unique target for a cholesterol lowering drug. Partial inhibition of OSC should reduce synthesis of lanosterol and subsequent sterols, and also stimulate the production of epoxysterols that repress HMG CoA reductase expression, generating a synergistic, self limited negative regulatory loop.
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