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Anti-proliferation effects
which are localized mainly in the perinuclear region of the replicon cells
4r)-4-[(1S)-2-[(5S)-6-fluoro-5H-imidazo[4
Chemical Name: 5-[2-(dimethylamino)ethoxy]-N-{3-[4-(hydroxycarbamoyl)phenyl]prop-2-yn-1-yl}-1H-indole-2-carboxamide
PIP4K-IN-a131 is PIP4K lipid kinases inhibitor
PF-3450074 60276 Anti-proliferation effectsPF 3450074 (PF 74) is a specifical inhibitor of HIV 1 capsid protein (CA) and displays a broad spectrum inhibition of HIV isolates with submicromolar potency (EC50=8 640 nM). PF 3450074 (PF 74) acts at an early stage of HIV 1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle. CPSF6: nuclear host factors