Pay in 4 interest-free payments of $8.00 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
2-hydroxyglutarate (2HG)
Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480
It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells
InChiKey: VAZAPHZUAVEOMC-UHFFFAOYSA-N
and used in cancer research
ABT-199 - BCL-2 inhibitor. CAS# 1257044-40-8 Catalog No.:M60075-10S 2-hydroxyglutarate (2HG)ABT 199, CAS No. 1257044 40 8, is a highly potent, selective, and orally bioavailable BCL 2 inhibitor. ABT 199 has picomolar affinity for BCL 2 (Ki < 0. 010 nM) and > 1000 folds selectivity over BCL XL (Ki = 48 nM) and BCL W (Ki = 245 nM). Therefore, ABT 199 is a much improved lead compound over the original ABT 263 (navitoclax) to avoid thrombocytopenia caused by BCL XL inhibition. ABT 199s cell killing effect is selective and mechanism dependent. It
US$ 700.00
US$ 600.00
US$ 700.00
US$ 600.00
US$ 900.00