ML-290 0191584 maleate which is potent and selective

which is potent and selective against BaF3-tel-c-KIT (IC50 of 4 nM) and a broad spectrum of drug-resistant mutants (IC50 of 8 nM for BaF3-tel-c-KIT-T670I) with improved bioavailability

4 and 290 nM at pH 8

SAFit1 (1-1000 nM) potently stimulates neurite outgrowth in two neuronal cell lines (N2a and SH-SY5Y) as well as in primary hippocampal neurons

tebanicline is an agonist

UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1

ML-290 0191584 maleate which is potent and selectiveML 290 is a first in class and potent relaxin insulin like family peptide receptor (RXFP1) agonist and activator of anti fibrotic genes, with an EC50 of 94 nM. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1. Product information CAS Number: 1482500 76 4 Molecular Weight: 506. 49 Formula: C24H21F3N2O5S Chemical Name: 2 (propan 2 yloxy) N {2 [(3 trifluoromethanesulfonylphenyl)carbamoyl]phenyl}benzamide Smiles: