3-Hydroxy Midostaurin - CAS# 179237-49-1 7895 Administration of SR9009 alters circadian

Administration of SR9009 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice

Terbinafine is a synthetic antifungal agent inhibiting fungal squalene epoxidase

1-2H3/b13-3+/t14-

Formula: C7H12N3NaO7S

Smiles: CC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=C/C(/NC1=O)=N\O

3-Hydroxy Midostaurin - CAS# 179237-49-1 7895 Administration of SR9009 alters circadian3 Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS like tyrosine kinase 3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9. 8 M in culture medium and plasma, respectively. 3 Hydroxy Midostaurin is less selective but more cytotoxic than PKC412. Product information CAS Number: 179237 49 1 Molecular Weight: 600. 66 Formula: C36H32N4O5 Chemical Name: N [(2R,4S,5S,7R) 17 hydroxy 5 methoxy 7 methyl 19 oxo