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L-2-Hydroxyglutaric acid Catalog No.:M15026-2 assays and selectively blocks proliferation

SKU: 3724385760

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Description

assays and selectively blocks proliferation of AML cell lines harboring FLT3-​ITD mutations

26)/t19-/m1/s1

Chemical Name: methyl N-[6-(benzenesulfinyl)-1H-1

3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-9

9(12):775-83

L-2-Hydroxyglutaric acid Catalog No.:M15026-2 assays and selectively blocks proliferationL 2 Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L 2 Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation. L 2 Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi CK) activity with Km and Ki of 2. 52 mM and 11. 13 mM, respectively. Product information CAS Number: 13095 48 2 Molecular Weight: 148. 11 Formula: C5H8O5 Chemical Name: (2S) 2

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