BI-4916 CC3)-1 NVR 3-778 is a first-in-Class

NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM (capsid assembly modulator) belonging to the SBA (sulfamoylbenzamide) class

InChi: InChI=1S/C23H17Cl2F3N2O4/c24-17-10-15(30-22(33)29-12-14-7-5-13(6-8-14)9-20(31)32)11-18(25)21(17)16-3-1-2-4-19(16)34-23(26

CAS Number: 1114544-31-8

3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase)

InChiKey: AAOLIMLEFKWKOY-IXMSMLDRSA-N

BI-4916 CC3)-1 NVR 3-778 is a first-in-ClassBI 4916 is a prodrug of BI 4924. BI 4924 is a NADH NAD+ competitive PHGDH inhibitor. Product information CAS Number: 2244451 48 5 Molecular Weight: 527. 42 Formula: C23H24Cl2N2O6S Chemical Name: ethyl 2 {4 [(1S) 1 [(4,5 dichloro 1,6 dimethyl 1H indol 2 yl)formamido] 2 hydroxyethyl]benzenesulfonyl}acetate Smiles: CC1=CC2=C(C=C(C(=O)N[C@H](CO)C3C=CC(=CC=3)S(=O)(=O)CC(=O)OCC)N2C)C(Cl)=C1Cl InChiKey: HCDAVCLCBXIYPW QGZVFWFLSA N InChi: InChI=1S