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RA190 stabilized targets of human papillomavirus (HPV) E6 oncoprotein
57(10):4213-38
Formula: C18H13ClF2N6O
likely occupying a similar site within the ligand-binding domain
Chemical Name: 3-(4-((4-fluoro-4'-methyl-[1
IM-12 - CAS# 1129669-05-1 Size:Solid 10 mg RA190 stabilized targets of humanIM 12 is a cell permeable indolylmaleimide that acts as a GSK 3 inhibitor. IM 12 is potent and selective enhances canonical Wnt signalling. IM 12 inhibits GSK 3 activity and subsequently increases catenin concentration significantly in hNPCs. When used to treat human neural progenitor cells, IM 12 promoted neuronal differentiation resulting in an increase of neuronal cells. Product information CAS Number: 1129669 05 1 Molecular Weight: 377. 41