N-Oxalylglycine taminyl Cyclase Inhibitor 2 1 nM in SK-OV-3 cells

1 nM in SK-OV-3 cells that calculated from the free fraction in the cell assay

Formula: C21H34O5

InChiKey: HMEDEBAJARCKCT-UHFFFAOYSA-N

Formula: C31H30FNO5

Bcl-2 expression fully blocks the activation of both initiator caspases as well as the effector caspase 3 in cells treated with activated Cyclophosphamide

N-Oxalylglycine taminyl Cyclase Inhibitor 2 1 nM in SK-OV-3 cellsThe jumonji domain containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are candidate anticancer agents as well as potential tools for elucidating the biological functions of JMJDs. 2 N Oxalylglycine, the amide