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SphK1 inhibitor II (SKI-II) inhibits acute myelogenous leukemia cell growth in vitro and in vivo
actinomycin I1
The highest Cariprazine dose produced significant sedation (72% inhibition for Cariprazine 1
It inhibits JARID1B (also known as KDM5B or PLU1) with an IC₅₀ of ~3 μM in vitro
The subcutaneous tumor growth of both T24 and HeLa cell xenografts treated with PAI-039 is markedly reduced compared with untreated controls
A3 HCl - CAS# 78957-85-4 yltransferase SphK1 inhibitor II (SKI-II) inhibitsA3 HCl, CAS No. 78957 85 4, is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK. Product information CAS Number: 78957 85 4 Molecular Weight: 321. 22 Formula: C12H14Cl2N2O2S Synonym: A 3 hydrochloride Chemical Name: N (2 Aminoethyl) 5 chloronaphthalene 1 sulfonamide hydrochloride Smiles: Cl. NCCNS(=O)(=O)C1=CC=CC2C1=CC=CC=2Cl InChiKey: VWAGIWCLJAQLAL UHFFFAOYSA N InChi: InChI=1S C12H13ClN2O2S. ClH c13 11 5 1 4 10 9(11)3 2 6
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