OXA-01 Catalog No.:M22527-C 5-dihydro-1H-pyrrol-1-yl)amino]-2-(trifluoromethyl)pyrimidine-5-carboxylate

5-dihydro-1H-pyrrol-1-yl)amino]-2-(trifluoromethyl)pyrimidine-5-carboxylate

Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor

The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure

β-naloxol β-naloxamine

Chemical Name: 2-[(2E)-3-(naphthalen-2-yl)but-2-enamido]benzoic acid

OXA-01 Catalog No.:M22527-C 5-dihydro-1H-pyrrol-1-yl)amino]-2-(trifluoromethyl)pyrimidine-5-carboxylateOXA 01 is an ATP competitive and selective inhibitor of both mTORC1 and mTORC2 with IC50 values of 29 nM and 7 nM, respectively . The mammalian target of rapamycin (mTOR) is a serine threonine kinase and exists in two complexes, mTORC1 and mTORC2. MTORC1 activation through PI3K and Akt controls cell growth and mTORC2 phosphorylates Akt, SGK1, and PKC to control cell survival and cytoskeletal organization . OXA 01 is a dual inhibitor of mTORC1 and