Gefitinib impurity 2 Catalog No.:M31681-C 3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7H

3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7H

Men 10376 is a selective tachykinin NK-2 receptor

InChiKey: KDAIMYGCILCZSH-FQEVSTJZSA-N

Smiles: CC1=NNC(=O)N1C1C=NC(=CC=1)OC1=CC=C(C)C2OCC3(CC3)C1=2

PF-04634817 (oral administration

Gefitinib impurity 2 Catalog No.:M31681-C 3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7HGefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY 50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity. Product information CAS Number: 246512 44 7 Molecular