CB1-IN-1 Catalog No.:M21313-C Smiles: CC(=O)OC(C)(C)C=CC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(C=C(O)C(=O)C4(C)C)C3(C)C(=O)CC21C

Smiles: CC(=O)OC(C)(C)C=CC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(C=C(O)C(=O)C4(C)C)C3(C)C(=O)CC21C

CAS Number: 113418-56-7

19-decaen-2-yl]acetamido}butanedioate

Smiles: COC1C=CC(=CC=1)C(OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1C=NC2C1=NC=NC=2NC(=O)C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC(=CC=1)OC

the drug does not need hepatic activation

CB1-IN-1 Catalog No.:M21313-C Smiles: CC(=O)OC(C)(C)C=CC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(C=C(O)C(=O)C4(C)C)C3(C)C(=O)CC21CCB1 IN 1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0. 3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0. 3 nM (Ki, CB1R) 21 nM (Ki, CB2R)Target: CB1Rin vivo: CB1 IN 1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight loss efficacy in diet induced obese mice. CB1 IN 1 has great potential to ameliorate this related metabolic syndrome. Product information CAS