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Topotecan Catalog No.:M9751-2 Chemical Name: 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1

SKU: 4204092680

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Description

Chemical Name: 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1

selective factor Xa inhibitor

EB-3D (1-40 μM

Niedziela-Majka A

19 mM) Ethanol 1

Topotecan Catalog No.:M9751-2 Chemical Name: 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I DNA covalent complexes, inhibiting religation of topoisomerase I mediated single strand DNA breaks and producing potentially lethal double strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline based alkaloid

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